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Disney's Alice In Wonderland is a monster hit. It clearly becomes the best March release ever with $45 million on Friday. If that holds up, the Tim Burton-directed, Johnny Depp starring fantasy flick could have a $115M-$120M opening weekend for the biggest 3D pic debut ever. (These numbers are blowing away Avatar's first weekend.)

The only other major newcomer this weekend was Overture's Brooklyn's Finest directed by Anton Fuqua and starring Richard Gere, Don Cheadle and Ethan Hawke opened like most R-rated action films: it had a $5.2M Friday for a likely $14.5M weekend.

Disney's Alice In Wonderland has a real shot at $100 million weekend.

Remember, those higher priced 3D tickets will make all the difference. Even so, the Tim Burton-directed, Johnny Depp-starring fantasy flick will certainly earn $75+M from its 3,728 locations this weekend. Its total domestic 3D count is 2,063 locations, plus 180 Imax 3D engagements, making it the largest 3D bow ever.

Overseas, Alice is expected to shoot to #1 after opening day and date in 40 territories beginning Wednesday.